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Hydrocodone is primarily used to manage pain that is moderate to severe and requires opioid analgesia. It is commonly prescribed for conditions such as acute injuries, post-surgical pain, and chronic pain conditions where other pain medications have been ineffective. Hydrocodone is a full opioid agonist, meaning it binds to and activates opioid receptors in the brain and spinal cord to produce its analgesic effects. It primarily acts on mu-opioid receptors, but it also affects other opioid receptor subtypes. Hydrocodone is often combined with other medications, such as acetaminophen (e.g., Vicodin, Norco) or ibuprofen (e.g., Vicoprofen), to enhance its pain-relieving effects. These combination products can provide synergistic pain relief and may allow for lower doses of hydrocodone, reducing the risk of adverse effects.