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One drug used to treat opioid addiction is methadone. It is a long-acting opioid agonist that functions by attaching itself to the same brain receptors as heroin and morphine. The effects of this binding are comparable to those of other opioids, including euphoria, sedation, and pain relief. Methadone can be taken less frequently than other opioids because its duration of action is longer. For this reason, methadone is a helpful drug to treat opioid addiction because it can lessen cravings and avoid withdrawal symptoms.

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